Williams is slated to star in the production until mid-April.
For a second time, the 29-year-old singer will play Roxie Hart, a role she first played in 'Chicago' on London's West End this past summer.
Williams was the first Black woman to star as Roxie on London's West End.
On Broadway, the Rockford, Illinois-bred vocalist will follow singer Ashlee Simpson, who is currently featured as Roxie.
Actress Renee Zelleweger played the role in the 2002 film adaptation of the Kander and Ebb musical set in prohibition era Chicago.
BV Buzz interviewed Williams this past summer in London and she said she was eager to play Roxie on Broadway.
"I would absolutely love to do 'Chicago' on Broadway! That's definitely a wish that I'd love to see come true," she told me then.
The 'Do You Know' and 'We Break The Dawn' singer starred on Broadway previously in the Elton John and Tim Rice-produced musical 'Aida,' a role that garnered her rave reviews.
Williams, who released her first pop CD 'Unexpected' last year, also starred as Shug Avery in the touring cast of the Oprah Winfrey-produced musical, 'The Color Purple,' which won her a NAACP Theatre Award for Best Lead Female Actress.
Calls to Williams' rep for comment were not returned at press time.
For related stories, read also: 'Razzle Dazzle: Michelle Williams Is London's First Black Roxie Hart'